Article
Lack of association of glutamate decarboxylase 2 gene polymorphisms with severe obesity in utah.
Obesity (Silver Spring, Md.) - 1 Apr 2006
Hunt Steven C, Xin Yuanpei, Wu Lily L, Hopkins Paul N, Adams Ted D
Abstract excerpt
Three polymorphisms of the glutamate decarboxylase 2 gene, which encodes the glutamic acid decarboxylase enzyme, have been associated with severe obesity in a large French cohort. One of these polymorphisms was shown to have functional consequences on promoter expression. Another polymorphism was associated with insulin levels and secretion. These associations were examined in 855 severely obese Utah subjects...
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