Article
Regulatory protein that inhibits both synthesis and use of the target protein controls flagellar phase variation in Salmonella enterica.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jul 2006
Aldridge Phillip D, Wu Cheng, Gnerer Joshua, Karlinsey Joyce E, Hughes Kelly T, Sachs Matthew S
Abstract excerpt
Flagellin is a major surface antigen for many bacterial species. The pathogen Salmonella enterica switches between two alternative, antigenic forms of its flagellin filament protein, either type B or C. This switching (flagellar phase variation) is achieved by stochastic inversion of a promoter that produces both type B flagellin (FljB) and an inhibitor (FljA) of type C flagellin formation. When the fljB-fljA...
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