The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme.

doi:10.1101/gad.12.19.3123

Back to search

Article

The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme.

Genes & development - 1 Oct 1998

Chadsey M S, Karlinsey J E, Hughes K T

Abstract excerpt

The anti-sigma factor FlgM of Salmonella typhimurium inhibits transcription of class 3 flagellar genes through a direct interaction with the flagellar-specific sigma factor, sigma28. FlgM is believed to prevent RNA polymerase (RNAP) holoenzyme formation by sequestering free sigma28. We have analy...

Topics

Bacterial Proteins
DNA, Fungal
DNA-Directed RNA Polymerases
Flagella
Glutathione Transferase
Kinetics
Mutation
Protein Binding
Repressor Proteins
Salmonella typhimurium
Sigma Factor

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.