Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme.

Genes & development - 1 Oct 1998

Chadsey M S, Karlinsey J E, Hughes K T

Abstract excerpt

The anti-sigma factor FlgM of Salmonella typhimurium inhibits transcription of class 3 flagellar genes through a direct interaction with the flagellar-specific sigma factor, sigma28. FlgM is believed to prevent RNA polymerase (RNAP) holoenzyme formation by sequestering free sigma28. We have analyzed FlgM-mediated inhibition of sigma28 activity in vitro. FlgM is able to inhibit sigma28 activity even when sigma28...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Fungal
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Mutation

Share to Protein Binding

Share to Repressor Proteins

Share to Salmonella typhimurium

Source

Open in PubMed Open full text

Identifiers

PMID: 9765212
DOI: 10.1101/gad.12.19.3123
PMCID: PMC317189

Genes

SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme.PMID 9765212Read ↗

The flagellar-specific transcription factor, sigma28, is the Type III secretion chaperone for the flagellar-specific anti-sigma28 factor FlgM.Semantic proximity Read ↗

Molecular characterization of flgM, a gene encoding a negative regulator of flagellin synthesis in Salmonella typhimurium.Semantic proximity Read ↗

Small RNAs OmrA and OmrB promote class III flagellar gene expression by inhibiting the synthesis of anti-Sigma factor FlgM.Semantic proximity Read ↗

The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, sigma 28.Semantic proximity Read ↗

Flk prevents premature secretion of the anti-sigma factor FlgM into the periplasm.Semantic proximity Read ↗

Cellular levels and activity of the flagellar sigma factor FliA of Escherichia coli are controlled by FlgM-modulated proteolysis.Semantic proximity Read ↗

The Helicobacter pylori anti-sigma factor FlgM is predominantly cytoplasmic and cooperates with the flagellar basal body protein FlhA.Semantic proximity Read ↗

Genetic and molecular analyses of the interaction between the flagellum-specific sigma and anti-sigma factors in Salmonella typhimurium.Semantic proximity Read ↗

Molecular dissection of the flagellum-specific anti-sigma factor, FlgM, of Salmonella typhimurium.Semantic proximity Read ↗

Flk couples flgM translation to flagellar ring assembly in Salmonella typhimurium.Semantic proximity Read ↗

Interaction between FliE and FlgB, a proximal rod component of the flagellar basal body of Salmonella.Semantic proximity Read ↗

Oligomerization of the bacterial flagellar ATPase FliI is controlled by its extreme N-terminal region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.