Article
Mapping functional domains of chloride intracellular channel (CLIC) proteins in vivo.
Journal of molecular biology - 23 Jun 2006
Berry Katherine L, Hobert Oliver
Abstract excerpt
Chloride intracellular channel (CLIC) proteins are small proteins distantly related to the omega family of glutathione S-transferases (GSTs). CLIC proteins are expressed in a wide variety of tissues in multicellular organisms and are targeted to specific cellular membranes. Members of this family are capable in vitro of changing conformation from a globular, soluble state to a membrane-inserted state in which...
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