V-myc immortalization of early rat neural crest cells yields a clonal cell line which generates both glial and adrenergic progenitor cells.

doi:10.1016/0012-1606(91)90220-w

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Article

V-myc immortalization of early rat neural crest cells yields a clonal cell line which generates both glial and adrenergic progenitor cells.

Developmental biology - 1 May 1991

Lo L C, Birren S J, Anderson D J

Abstract excerpt

We describe the isolation and characterization of an immortal cell line derived by infection of rat neural crest cells with a v-myc-containing replication-defective retrovirus. This clonal cell line, called NCM-1, contains a majority cell population with antigenic and morphologic properties that suggest it may represent a peripheral glial progenitor. In conditioned or in serum-free medium, these NGF...

Topics

Animals
Cell Differentiation
Cell Line
Cell Transformation, Viral
Cells, Cultured
Clone Cells
Dexamethasone
Fetus
Fibroblast Growth Factor 2
Genes, myc
Glial Fibrillary Acidic Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Intermediate Filament Proteins

Laminin

Nerve Growth Factors

Neural Crest

Neurofilament Proteins

Neuroglia

Source

Open in PubMed

Identifiers

PMID: 1673438
DOI: 10.1016/0012-1606(91)90220-w

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1673438-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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