Article
Olfactory neuronal cell lines generated by retroviral insertion of the n-myc oncogene display different developmental phenotypes.
Journal of neuroscience research - 1 Aug 1996
MacDonald K P, Mackay-Sim A, Bushell G R, Bartlett P F
Abstract excerpt
Being genetically homogeneous, clonal cell lines are potentially important for investigating many aspects of cellular differentiation. We describe here the creation of clonal cell lines by immortalization of neuronal precursor cells from the adult mouse olfactory epithelium. Unlike neurons elsewhere in the vertebrate nervous system, the olfactory sensory neuron can be replaced throughout the lifespan of the...
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