Article
Membrane cofactor protein of the complement system. A HindIII restriction fragment length polymorphism that correlates with the expression polymorphism.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1991
Bora N S, Post T W, Atkinson J P
Abstract excerpt
An RFLP was found in the DNA of 25 unrelated persons, two families, and five cell lines that correlated with their membrane cofactor protein phenotype. If restricted with HindIII, DNA derived from upper band predominant protein (U) phenotypes had a band at 2 kb, whereas DNA of lower band predominant (L) phenotypes had a 4-kb band. The equal band protein phenotype, in which equal quantities of the two species are...
Topics
- Alleles
- Antigens, CD
- Base Sequence
- Deoxyribonuclease HindIII
- Humans
- Membrane Cofactor Protein
- Membrane Glycoproteins
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length