Article
Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation.
The Journal of biological chemistry - 28 Jul 2006
Richardson Richard T, Alekseev Oleg M, Grossman Gail, Widgren Esther E, Thresher Randy, Wagner Eric J, Sullivan Kelly D, Marzluff William F, O'Rand Michael G
Abstract excerpt
A multichaperone nucleosome-remodeling complex that contains the H1 linker histone chaperone nuclear autoantigenic sperm protein (NASP) has recently been described. Linker histones (H1) are required for the proper completion of normal development, and NASP transports H1 histones into nuclei and exchanges H1 histones with DNA. Consequently, we investigated whether NASP is required for normal cell cycle progression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
