Article
Adhesion of Pseudomonas aeruginosa pilin-deficient mutants to mucin.
Infection and immunity - 1 Apr 1991
Ramphal R, Koo L, Ishimoto K S, Totten P A, Lara J C, Lory S
Abstract excerpt
Attachment of Pseudomonas aeruginosa to epithelial cells or tracheobronchial mucin is mediated by surface adhesins. Pili, composed of monomeric pilin subunits, make up one such class of adhesins. The formation of pili and flagella in P. aeruginosa is under the control of the alternative sigma factor rpoN. Isogenic mutant strains with insertionally inactivated rpoN genes were constructed with strains PAK, 1244,...
Topics
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- Hemagglutination
- Humans
- Mucins
- Mutation
- Pseudomonas aeruginosa
