Article
Influence of pilin glycosylation on Pseudomonas aeruginosa 1244 pilus function.
Infection and immunity - 1 Dec 2005
Smedley James G, Jewell Erica, Roguskie Jennifer, Horzempa Joseph, Syboldt Andrew, Stolz Donna Beer, Castric Peter
Abstract excerpt
The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial pneumonia. Among its virulence factors, the type IV pili of P. aeruginosa strain 1244 contain a covalently linked, three-sugar glycan of previously unknown significance. The work described in this paper was carried out to determine the influence of the P. aeruginosa 1244 pilin glycan on pilus function, as well as a possible role in...
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