Article
Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8.
The Journal of clinical investigation - 1 Nov 1995
DiMango E, Zar H J, Bryan R, Prince A
Abstract excerpt
Respiratory epithelial cells play a crucial role in the inflammatory response during Pseudomonas aeruginosa infection in the lungs of patients with cystic fibrosis. In this study, we determined whether the binding of specific Pseudomonas gene products (pilin, flagellin) to their receptors on resp...
Topics
- Adhesins, Bacterial
- Bacterial Outer Membrane Proteins
- Base Sequence
- Cell Line, Transformed
- Epithelium
- Fimbriae Proteins
- Flagellin
- Humans
- Interleukin-8
- Molecular Sequence Data
- Mutation
- Pseudomonas aeruginosa
- Respiratory System