Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross.

doi:10.1016/0888-7543(91)90232-4

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Article

Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross.

Genomics - 1 Jan 1991

Norman D J, Fletcher C, Heintz N

Abstract excerpt

The lurcher (Lc) mutant mouse strain exhibits postnatal degeneration of cerebellar Purkinje cells. We have typed progeny from an intersubspecific, phenotypic backcross at seven loci to develop a genetic linkage map which spans approximately 35 cM surrounding and including the Lc locus on mouse ch...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Genetic Linkage
Mice
Mice, Neurologic Mutants
Mutation
Polymorphism, Restriction Fragment Length

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