Article
Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross.
Genomics - 1 Jan 1991
Norman D J, Fletcher C, Heintz N
Abstract excerpt
The lurcher (Lc) mutant mouse strain exhibits postnatal degeneration of cerebellar Purkinje cells. We have typed progeny from an intersubspecific, phenotypic backcross at seven loci to develop a genetic linkage map which spans approximately 35 cM surrounding and including the Lc locus on mouse chromosome 6. [(Mus musculus castaneus x B6CBA-Aw-J/A-Lc)F1 x B6CBA-Aw-J/A]N2 progeny were scored visually for the...
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