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Article

Double bolt regulation of Rad51 by p53: a role for transcriptional repression.

Cell cycle (Georgetown, Tex.) - 1 May 2006

Lazaro-Trueba Iciar, Arias Carmen, Silva Augusto

Abstract excerpt

The regulation of homologous recombination (HR) by p53 has been currently associated with its nontransactivating function; now the transcriptional repression of the Rad51 gene by p53 has been elucidated. This extra control by p53 involves the transcriptional downregulation of Rad51 protein, which in turn accounts for the reduction of functional Rad51 foci. Down regulation of Rad51 protein might be relevant,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 16721049
DOI: 10.4161/cc.5.10.2764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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