Article
In vitro propagation of spermatogonial stem cells from KM mice.
Frontiers in bioscience : a journal and virtual library - 1 Sept 2006
Shi Yu-Qiang, Wang Qing-Zhong, Liao Shang-Ying, Zhang Yan, Liu Yi-Xun, Han Chun-Sheng
Abstract excerpt
Spermatogonial stem cells (SSCs) are a unique type of stem cells in that they transmit genetic information to the next generation by producing sperms. Studies of SSC proliferation and differentiation have been hampered by the inability of reconstructing these processes in vitro, particularly in a serum-free culture system. Several groups have reported the long term culture of SSCs during which SSCs self-renew and...
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