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Article

CYP induction-mediated drug interactions: in vitro assessment and clinical implications.

Pharmaceutical research - 1 Jun 2006

Lin Jiunn H

Abstract excerpt

Cytochrome P450 (CYP) induction-mediated interaction is one of the major concerns in clinical practice and for the pharmaceutical industry. There are two major issues associated with CYP induction: a reduction in therapeutic efficacy of comedications and an induction in reactive metabolite-induced toxicity. Because CYP induction is a metabolic liability in drug therapy, it is highly desirable to develop new drug...

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Source

Identifiers

PMID: 16718615
DOI: 10.1007/s11095-006-0277-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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