Article
Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary artery disease in Arabs.
Human biology - 1 Dec 2005
Abu-Amero Khaled K, Al-Boudari Olayan M, Mohamed Gamal H, Dzimiri Nduna
Abstract excerpt
The substitution of tryptophan (Trp) by arginine (Arg) at position 64 in the beta3-adrenoceptor (beta3-AR) gene has been associated with obesity, diabetes mellitus, and coronary artery disease (CAD). We have investigated whether the Trp64Arg polymorphism is associated with the manifestation of CAD or one of its important risk factors, such as obesity, diabetes mellitus, elevated cholesterol and triglyceride...
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