Article
Lack of association between microsatellite instability and benign adrenal tumors.
World journal of surgery - 1 Jul 2006
Namour Fares, Ayav Ahmet, Lu Xiaohong, Klein Marc, Muresan Miahela, Bresler Laurent, Tramoy Denise, Guéant Jean-Louis, Brunaud Laurent
Abstract excerpt
BACKGROUND: The adrenal gland may give rise to pheochromocytomas, which are catecholamine-producing tumors originating from the adrenal medulla, or to adrenocortical tumors, which derive from the adrenocortical cortex and may be secreting or not. The genetic mechanisms underlying the formation of these tumors include somatic mutations in susceptibility genes, especially in the familial forms, and allelic loss,...
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