Article
C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates.
Development (Cambridge, England) - 1 Jul 2006
Andersen Erik C, Lu Xiaowei, Horvitz H Robert
Abstract excerpt
The class A, B and C synthetic multivulva (synMuv) genes act redundantly to negatively regulate the expression of vulval cell fates in Caenorhabditis elegans. The class B and C synMuv proteins include homologs of proteins that modulate chromatin and influence transcription in other organisms simi...
Topics
- Adenosine Triphosphatases
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Lineage
- Chromatin
- Chromosomal Proteins, Non-Histone
- Drosophila Proteins
- Humans
- Morphogenesis
- Multiprotein Complexes
- Phenotype
- RNA Interference
- Retinoblastoma Protein
- Signal Transduction
- Transcription Factors
- ras Proteins