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Epstein-Barr virus-positive gastric cancer: a distinct molecular subtype of the disease?

1 Apr 2016

Abstract excerpt

Approximately 90% of the world population is infected by Epstein-Barr virus (EBV). Usually, it infects B lymphocytes, predisposing them to malignant transformation. Infection of epithelial cells occurs rarely, and it is estimated that about to 10% of gastric cancer patients harbor EBV in their malignant cells. Given that gastric cancer is the third leading cause of cancer-related mortality worldwide, with a...

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PMID: 27192582
DOI: 10.1590/0037-8682-0270-2015

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