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Article

Promoter hypermethylation of E-cadherin and its abnormal expression in Epstein-Barr virus-associated gastric carcinoma.

International journal of cancer - 20 Mar 2004

Sudo Makoto, Chong Ja-Mun, Sakuma Kazuya, Ushiku Tetsuo, Uozaki Hiroshi, Nagai Hideo, Funata Nobuaki, Matsumoto Yoshiro, Fukayama Masashi

Abstract excerpt

Promoter hypermethylation of various tumor-related genes is extremely frequent in Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC). To investigate the significance of the promoter methylation in EBVaGC, we focused on one of the important proteins in the carcinogenesis of the stomach, E-cadherin. Methylation-specific PCR analysis (MSP) was applied to surgically resected gastric carcinomas, together...

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Identifiers

PMID: 14750169
DOI: 10.1002/ijc.11701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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