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Article

Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth.

The Journal of biological chemistry - 28 Jul 2006

Patwardhan Parag, Shen Yongquan, Goldberg Gary S, Miller W Todd

Abstract excerpt

Cas is a multidomain signaling protein that resides in focal adhesions. Cas possesses a large central substrate domain containing 15 repeats of the sequence YXXP, which are phosphorylated by Src. The phosphorylation sites are essential for the roles of Cas in cell migration and in regulation of t...

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Identifiers

PMID: 16707485
DOI: 10.1074/jbc.M602311200
PMCID: PMC2441569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16707485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth.PMID 16707485Read ↗

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