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Article

Role of genes, the environment and their interactions in the etiology of inflammatory bowel diseases.

Expert review of molecular diagnostics - 1 May 2006

Ahmed Farid E

Abstract excerpt

Few of the studied genes demonstrate association with inflammatory bowel disease (IBD). Three mutations in the nucleotide-binding oligomerization domain 2 gene have consistently shown to be independent risk factors for Crohn's disease, but none of the alleles exhibited high sensitivity or specificity for IBD. Linkage analysis implicated several loci on various chromosomes, and epistasis has been demonstrated. The...

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Identifiers

PMID: 16706738
DOI: 10.1586/14737159.6.3.345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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