Article
Gene-environment interactions in inflammatory bowel disease pathogenesis.
Current opinion in gastroenterology - 1 Jul 2015
Wang Ming-Hsi, Achkar Jean-Paul
Abstract excerpt
PURPOSE OF REVIEW: Inflammatory bowel disease (IBD) has long been known to have genetic risk factors because of increased prevalence in the relatives of affected individuals. However, genome-wide association studies have only explained limited heritability in IBD. The observed globally rising incidence of IBD has implicated the role of environmental factors. The hidden unexplained heritability remains to be...
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