Article
SWI/SNF binding to the HO promoter requires histone acetylation and stimulates TATA-binding protein recruitment.
Molecular and cellular biology - 1 Jun 2006
Mitra Doyel, Parnell Emily J, Landon Jack W, Yu Yaxin, Stillman David J
Abstract excerpt
We use chromatin immunoprecipitation assays to show that the Gcn5 histone acetyltransferase in SAGA is required for SWI/SNF association with the HO promoter and that binding of SWI/SNF and SAGA are interdependent. Previous results showed that SWI/SNF binding to HO was Gcn5 independent, but that work used a strain with a mutation in the Ash1 daughter-specific repressor of HO expression. Here, we show that Ash1...
Topics
- Acetylation
- Adenosine Triphosphatases
- Alleles
- Catalysis
- Cell Cycle Proteins
- Chromosomal Proteins, Non-Histone
- DNA-Binding Proteins
- Deoxyribonucleases, Type II Site-Specific
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Histone Acetyltransferases
- Histone Deacetylases