Article
Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene.
Cell - 8 Mar 1996
Sil A, Herskowitz I
Abstract excerpt
S. cerevisiae cells exhibit asymmetric determination of cell fate. Cell division yields a mother cell, which is competent to transcribe the HO gene and switch mating type, and a daughter cell, which is not. We have isolated a mutant in which daughters transcribe HO and switch mating type. This mu...
Topics
- Amino Acid Sequence
- Cloning, Molecular
- DNA-Binding Proteins
- Deoxyribonucleases, Type II Site-Specific
- Ethyl Methanesulfonate
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genotype
- Mitosis
- Models, Biological
- Molecular Sequence Data
- Mutagenesis
- Mutagens
- Recombinant Proteins
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid