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Article

The communal relation of MTHFR, MTR, ACE gene polymorphisms and hyperhomocysteinemia as conceivable risk of coronary artery disease.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme - 1 Oct 2017

Masud Rizwan, Baqai Haider Zaigham

Abstract excerpt

Homocysteine and its modulating genes have strongly emerged as novel biomarkers for coronary artery disease (CAD). In the present study, we investigated whether polymorphisms in homocysteine pathway genes and the plasma levels of homocysteine, folate, and vitamin B12, independently or in combination, are associated with CAD risk. A total of 504 participants were recruited (cases, n = 254; controls, n = 250,...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperhomocysteinemia

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Peptidyl-Dipeptidase A

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Source

Identifiers

PMID: 28514598
DOI: 10.1139/apnm-2017-0030

Genes

CAD
ACE
MTHFR
MTR
CBS
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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