Article
Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2006
Hebbring Scott J, Fredriksson Henna, White Kirsten A, Maier Christiane, Ewing Charles, McDonnell Shannon K, Jacobsen Steven J, Cerhan James, Schaid Daniel J, Ikonen Tarja, Autio Ville, Tammela Teuvo L J, Herkommer Kathleen, Paiss Thomas, Vogel Walther, Gielzak Marta, Sauvageot Jurga, Schleutker Johanna, Cooney Kathleen A, Isaacs William, Thibodeau Stephen N
Abstract excerpt
The Nijmegen breakage syndrome 1 (NBS1) gene, which participates in DNA double strand break repair, has been postulated to be a susceptibility factor for a number of cancers, including prostate cancer. Numerous mutations have been identified in NBS1, including the founder mutation 657del5. In thi...
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