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Article

Inherited NBN Mutations and Prostate Cancer Risk and Survival

27 Dec 2018

Abstract excerpt

PURPOSE: To establish the contribution of four founder alleles of NBN to prostate cancer risk and cancer survival. MATERIALS AND METHODS: Five thousand one hundred eighty-nine men with prostate cancer and 6,152 controls were genotyped for four recurrent variants of NBN (657del5, R215W, I171V, and E185Q). RESULTS: The NBN 657del5 mutation was detected in 74 of 5,189 unselected cases and in 35 of 6,152 controls...

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PMID: 30590007
DOI: 10.4143/crt.2018.532

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