Article
Phosphatidylserine is involved in gene expression from Sindbis virus subgenomic promoter.
Biochemical and biophysical research communications - 30 Jun 2006
Saito Kyoko, Nishijima Masahiro, Kuge Osamu
Abstract excerpt
Sindbis virus replication is mediated by an RNA replicase translated from viral RNA genome. The replicase synthesizes progeny genomic RNA and shorter RNA (subgenomic RNA) carrying viral structural genes in association with cytoplasmic membranes. Here we examined the involvement of a membrane lipid, phosphatidylserine (PS), in Sindbis virus gene expression using Chinese hamster ovary cell mutants. When the mutant...
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