Article
Decreased density of serotonin 5-HT2A receptors in rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Jun 2006
Kling A, Rantapää-Dahlqvist S, Stenlund H, Mjörndal T
Abstract excerpt
BACKGROUND: Animal studies have indicated that 5-HT2A receptors could play a role in arthritic diseases. OBJECTIVE: To analyse the binding properties of 5-HT2A receptors in patients with rheumatoid arthritis. METHODS: Using a radioactive binding assay, 43 patients with rheumatoid arthritis were compared with 49 sex and age matched controls for density and affinity (measured as Bmax and Kd) of 5-HT2A serotonin...
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