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Wnt Signaling Regulates the Invasion Capacity of Human Mesenchymal Stem Cells

12 May 2006

Abstract excerpt

Human mesenchymal stem cells (hMSCs) exhibit the potential to contribute to a wide variety of endogenous organ tissue repair. However, the signals governing hMSC mobilization out of the bone marrow, release into the bloodstream, and migration/invasion into the target tissue are largely unknown. Since canonical Wnt signaling regulates not only tumor but also various stem cell attributes, we hypothesized that this...

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PMID: 16690780
DOI: 10.1634/stemcells.2005-0503

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