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Article

HLA class I deficiencies due to mutations in subunit 1 of the peptide transporter TAP1.

The Journal of clinical investigation - 1 Mar 1999

de la Salle H, Zimmer J, Fricker D, Angenieux C, Cazenave J P, Okubo M, Maeda H, Plebani A, Tongio M M, Dormoy A, Hanau D

Abstract excerpt

The transporter associated with antigen processing (TAP), which is composed of two subunits (TAP1 and TAP2) that have different biochemical and functional properties, plays a key role in peptide loading and the cell surface expression of HLA class I molecules. Three cases of HLA class I deficienc...

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Topics

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10074495
DOI: 10.1172/JCI5687
PMCID: PMC408129

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10074495-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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