Article
Platelet-activating factor-acetylhydrolase A379V (exon 11) gene polymorphism is an independent and functional risk factor for premature myocardial infarction.
Journal of thrombosis and haemostasis : JTH - 1 May 2006
Liu P-Y, Li Y-H, Wu H-L, Chao T-H, Tsai L-M, Lin L-J, Shi G-Y, Chen J-H
Abstract excerpt
BACKGROUND: Oxidation of low density lipoproteins is an initial step of atherogenesis that generates pro-inflammatory phospholipids, including platelet-activating factor (PAF). PAF is degraded by PAF-acetylhydrolase (PAF-AH), which has been postulated to be a risk factor for myocardial infarction...
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