Apolipoprotein E ɛ3/ɛ4 genotype is associated with premature myocardial infarction: a hospital based retrospective study.

doi:10.1186/s12872-026-05513-5

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Article

Apolipoprotein E ɛ3/ɛ4 genotype is associated with premature myocardial infarction: a hospital based retrospective study.

BMC cardiovascular disorders - 15 Jan 2026

Wang Hao, Li Bin, Chen Wenhao, Wei Guoliang, Chen Kehui, Wang Weihong, Liu Yuanliang

Abstract excerpt

OBJECTIVE: To explore the association between apolipoprotein E (APOE) gene polymorphisms and the risk of premature (age of onset: men ≤ 55 years old, women ≤ 65 years old) myocardial infarction (PMI). METHODS: This study retrospectively collected the medical records (age, gender, hypertension, diabetes mellitus, smoking, drinking, and serum lipid) of 379 PMI patients and 628 age-matched non-AMI individuals...

Topics

Humans
Retrospective Studies
Genetic Predisposition to Disease
Myocardial Infarction
Middle Aged
Apolipoprotein E4
Risk Factors
Male
Female
Apolipoprotein E3
Risk Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Phenotype

Genetic Association Studies

Age of Onset

Adult

Gene Frequency

China

Source

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Identifiers

PMID: 41540357
DOI: 10.1186/s12872-026-05513-5
PMCID: PMC12892622

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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