Article
Multilocus effects of the renin-angiotensin-aldosterone system genes on blood pressure response to a thiazide diuretic.
The pharmacogenomics journal - 1 Jan 2004
Frazier L, Turner S T, Schwartz G L, Chapman A B, Boerwinkle E
Abstract excerpt
BACKGROUND: The renin-angiotensin-aldosterone (RAA) system regulates blood pressure (BP) levels and influences responses to antihypertensive medications. Variation in RAA system genes has been reported to influence interindividual differences in BP levels and the occurrence of hypertension (HTN)....
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