Article
Differential expression of platelet glycoprotein Ia/IIa in Taiwan Chinese corresponds to glycoprotein ia gene polymorphisms.
Journal of pharmacological sciences - 1 May 2006
Liu Chao-Zong, Wang Yi-Chai, Wang Ji-Hung, Shaw Cheng-Kuang, Lin Gang-Ling
Abstract excerpt
Glycoprotein (GP) Ia/IIa plays a key role in platelet function by acting as a primary receptor for subendothelial collagen, thereby contributing to arterial thrombosis. In this study, we found that the expression level of platelet GPIa/IIa among Taiwan Chinese varies over sixfold and this difference relates either to the GPIa gene 807 C/T dimorphisms or the appearance of BglII restriction sequence within intron...
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