Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KRAS mutational analysis in ductal adenocarcinoma of the pancreas and its clinical significance.

Pathology, research and practice - 1 May 2014

Miglio Umberto, Oldani Alberto, Mezzapelle Rosanna, Veggiani Claudia, Paganotti Alessia, Garavoglia Marcello, Boldorini Renzo

Abstract excerpt

Mutations of KRAS are detectable in 70-90% of pancreatic duct adenocarcinomas (PDAC), using direct sequencing. We used a highly sensitive molecular method in order to investigate: (a) the frequency and prognostic significance of different KRAS mutations and, (b) whether the presence of KRAS mutat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, ras

Share to Neoplasm Recurrence, Local

Share to Pancreas

Share to Pancreatic Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 24629489
DOI: 10.1016/j.prp.2014.01.011

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24629489-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KRAS mutational analysis in ductal adenocarcinoma of the pancreas and its clinical significance.PMID 24629489Read ↗

Prognostic Properties of KRAS Gene Mutation Subtypes in Resected Pancreatic Ductal Adenocarcinoma.Semantic proximity Read ↗

Somatic Mutations in Exocrine Pancreatic Tumors: Association with Patient SurvivalSemantic proximity Read ↗

KRAS gene mutation quantification in the resection or venous margins of pancreatic ductal adenocarcinoma is not predictive of disease recurrence.Semantic proximity Read ↗

Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer.Semantic proximity Read ↗

Prognostic value of KRAS gene mutations in pancreatic ductal adenocarcinoma: a systematic review and meta-analysis.Semantic proximity Read ↗

KRAS gene mutation quantification in the resection or venous margins of pancreatic ductal adenocarcinoma is not predictive of disease recurrenceSemantic proximity Read ↗

Prognostic Role of Specific KRAS Mutations Detected in Aspiration and Liquid Biopsies from Patients with Pancreatic Cancer.Semantic proximity Read ↗

KRAS G12D Mutation Subtype in Pancreatic Ductal Adenocarcinoma: Does It Influence Prognosis or Stage of Disease at Presentation?Semantic proximity Read ↗

Plasma KRAS mutations predict the early recurrence after surgical resection of pancreatic cancer.Semantic proximity Read ↗

Preoperative detection of KRAS G12D mutation in ctDNA is a powerful predictor for early recurrence of resectable PDAC patients.Semantic proximity Read ↗

Impact of KRAS Mutations and Co-mutations on Clinical Outcome in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Survival in ampullary cancer: potential role of different KRAS mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.