Article
Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila.
Current biology : CB - 9 May 2006
Carbone Mary Anna, Jordan Katherine W, Lyman Richard F, Harbison Susan T, Leips Jeff, Morgan Theodore J, DeLuca Maria, Awadalla Philip, Mackay Trudy F C
Abstract excerpt
Quantitative traits are shaped by networks of pleiotropic genes . To understand the mechanisms that maintain genetic variation for quantitative traits in natural populations and to predict responses to artificial and natural selection, we must evaluate pleiotropic effects of underlying quantitative trait genes and define functional allelic variation at the level of quantitative trait nucleotides (QTNs)....
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