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Article

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep.

Nature genetics - 1 Mar 2009

Harbison Susan T, Carbone Mary Anna, Ayroles Julien F, Stone Eric A, Lyman Richard F, Mackay Trudy F C

Abstract excerpt

Sleep disorders are common in humans, and sleep loss increases the risk of obesity and diabetes. Studies in Drosophila have revealed molecular pathways and neural tissues regulating sleep; however, genes that maintain genetic variation for sleep in natural populations are unknown. Here, we characterized sleep in 40 wild-derived Drosophila lines and observed abundant genetic variation in sleep architecture. We...

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Identifiers

PMID: 19234472
DOI: 10.1038/ng.330
PMCID: PMC2683981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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