Article
Partial interferon-gamma receptor deficiency and non-tuberculous mycobacterial lung disease.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2006
Hwang Jung Hye, Koh Won-Jung, Kim Eun Joo, Kang Eun Hae, Suh Gee Young, Chung Man Pyo, Kim Hojoong, Kwon O Jung
Abstract excerpt
Interferon-gamma (IFN-gamma) plays a key role in the host defense response against mycobacterial disease, and a complete or partial deficiency in IFN-gamma receptor 1 (IFN-gammaR1) or IFN-gamma receptor 2 (IFN-gammaR2) has been reported to contribute to susceptibility to disseminated infection with non-tuberculous mycobacteria (NTM). However, IFN-gammaR1 and IFN-gammaR2 deficiencies have not yet been studied in...
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