Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation.

The Journal of biological chemistry - 14 Jul 2006

Narayanan Karthikeyan, Gajjeraman Sivakumar, Ramachandran Amsaveni, Hao Jianjun, George Anne

Abstract excerpt

Dentin mineralization requires transcriptional mechanisms to induce a cascade of gene expression for progressive development of the odontoblast phenotype. During cytodifferentiation of odontoblasts there is a constant change of actively transcribed genes. Thus, tissue-specific matrix genes that are silenced in early differentiation are expressed during the terminal differentiation process. Dentin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix

Share to Extracellular Matrix Proteins

Share to Phosphoproteins

Share to Plasmids

Share to Protein Structure, Tertiary

Share to Sialoglycoproteins

Source

Identifiers

PMID: 16679514
DOI: 10.1074/jbc.M600714200

Genes

DMP1
DSPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation.PMID 16679514Read ↗

Dentin Matrix Protein 1, a Target Molecule for Cbfa1 in Bone, Is a Unique Bone Marker GeneSemantic proximity Read ↗

Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues.Semantic proximity Read ↗

Dentin sialophosphoprotein in biomineralization.Semantic proximity Read ↗

The odontoblastic differentiation of dental mesenchymal stem cells: molecular regulation mechanism and related genetic syndromesSemantic proximity Read ↗

Elucidating epigenetic mechanisms governing odontogenic differentiation in dental pulp stem cells: an in-depth explorationSemantic proximity Read ↗

Molecular basis of human dentin diseases.Semantic proximity Read ↗

Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype.Semantic proximity Read ↗

Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype.Semantic proximity Read ↗

Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null mice.Semantic proximity Read ↗

Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice.Semantic proximity Read ↗

Compromised alveolar bone cells in a patient with dentinogenesis imperfecta caused by DSPP mutation.Semantic proximity Read ↗

Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.