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Article

Differential suppression of priA2::kan phenotypes in Escherichia coli K-12 by mutations in priA, lexA, and dnaC.

Genetics - 1 May 1996

Sandler S J, Samra H S, Clark A J

Abstract excerpt

First identified as an essential component of the phi X174 in vitro DNA replication system, PriA has ATPase, helicase, translocase, and primosome-assembly activities. priA1::kan strains of Escherichia coli are sensitive to UV irradiation, deficient in homologous recombination following transduction, and filamentous. priA2::kan strains have eightfold higher levels of uninduced SOS expression than wild type. We...

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Identifiers

PMID: 8722757
DOI: 10.1093/genetics/143.1.5
PMCID: PMC1207281

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential suppression of priA2::kan phenotypes in Escherichia coli K-12 by mutations in priA, lexA, and dnaC.PMID 8722757Read ↗

dnaC mutations suppress defects in DNA replication- and recombination-associated functions in priB and priC double mutants in Escherichia coli K-12.Semantic proximity Read ↗

The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair.Semantic proximity Read ↗

Purification and characterization of DnaC810, a primosomal protein capable of bypassing PriA function.Semantic proximity Read ↗

Escherichia coli K-12 has two distinguishable PriA-PriB replication restart pathways.Semantic proximity Read ↗

Mutational Analysis of Residues in PriA and PriC Affecting Their Ability To Interact with SSB in Escherichia coli K-12.Semantic proximity Read ↗

A novel dnaC mutation that suppresses priB rep mutant phenotypes in Escherichia coli K-12.Semantic proximity Read ↗

Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response.Semantic proximity Read ↗

PriA mutations that affect PriA-PriC function during replication restart.Semantic proximity Read ↗

Multiple genetic pathways for restarting DNA replication forks in Escherichia coli K-12.Semantic proximity Read ↗

ATPase/helicase motif mutants of Escherichia coli PriA protein essential for recombination-dependent DNA replication.Semantic proximity Read ↗

Modulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12.Semantic proximity Read ↗

A dnaT mutant with phenotypes similar to those of a priA2::kan mutant in Escherichia coli K-12.Semantic proximity Read ↗

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