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MreB of Streptomyces coelicolor is not essential for vegetative growth but is required for the integrity of aerial hyphae and spores.

Molecular microbiology - 1 May 2006

Mazza Paola, Noens Elke E, Schirner Kathrin, Grantcharova Nina, Mommaas A Mieke, Koerten Henk K, Muth Günther, Flärdh Klas, van Wezel Gilles P, Wohlleben Wolfgang

Abstract excerpt

MreB forms a cytoskeleton in many rod-shaped bacteria which is involved in cell shape determination and chromosome segregation. PCR-based and Southern analysis of various actinomycetes, supported by analysis of genome sequences, revealed mreB homologues only in genera that form an aerial mycelium and sporulate. We analysed MreB in one such organism, Streptomyces coelicolor. Ectopic overexpression of mreB impaired...

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PMID: 16677297
DOI: 10.1111/j.1365-2958.2006.05134.x

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MreB of Streptomyces coelicolor is not essential for vegetative growth but is required for the integrity of aerial hyphae and spores.PMID 16677297Read ↗

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