Article
Dysfunctional MreB inhibits chromosome segregation in Escherichia coli.
The EMBO journal - 1 Oct 2003
Kruse Thomas, Møller-Jensen Jakob, Løbner-Olesen Anders, Gerdes Kenn
Abstract excerpt
The mechanism of prokaryotic chromosome segregation is not known. MreB, an actin homolog, is a shape-determining factor in rod-shaped prokaryotic cells. Using immunofluorescence microscopy we found that MreB of Escherichia coli formed helical filaments located beneath the cell surface. Flow cytom...
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