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Article

Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.

Science (New York, N.Y.) - 8 Jul 2011

Domínguez-Escobar Julia, Chastanet Arnaud, Crevenna Alvaro H, Fromion Vincent, Wedlich-Söldner Roland, Carballido-López Rut

Abstract excerpt

The peptidoglycan cell wall and the actin-like MreB cytoskeleton are major determinants of cell shape in rod-shaped bacteria. The prevailing model postulates that helical, membrane-associated MreB filaments organize elongation-specific peptidoglycan-synthesizing complexes along sidewalls. We used total internal reflection fluorescence microscopy to visualize the dynamic relation between MreB isoforms and cell...

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PMID: 21636744
DOI: 10.1126/science.1203466

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