The product of a developmental gene, crgA, that coordinates reproductive growth in Streptomyces belongs to a novel family of small actinomycete-specific proteins.

Abstract excerpt

On solid media, the reproductive growth of Streptomyces involves antibiotic biosynthesis coincident with the erection of filamentous aerial hyphae. Following cessation of growth of an aerial hypha, multiple septation occurs at the tip to form a chain of unigenomic spores. A gene, crgA, that coordinates several aspects of this reproductive growth is described. The gene product is representative of a well-conserved...

Topics

• Actinobacteria
• Amino Acid Sequence
• Bacterial Proteins
• Cell Division
• Culture Media
• Gene Expression Regulation, Bacterial
• Genes
• Genes, Developmental
• Genetic Complementation Test
• Membrane Proteins
• Molecular Sequence Data
• Mutation
• Spores, Bacterial