Article
GENOMIZER: an integrated analysis system for genome-wide association data.
Human mutation - 1 Jun 2006
Franke Andre, Wollstein Andreas, Teuber Markus, Wittig Michael, Lu Tim, Hoffmann Katrin, Nürnberg Peter, Krawczak Michael, Schreiber Stefan, Hampe Jochen
Abstract excerpt
Genome-wide association analysis appears to be a promising way to identify heritable susceptibility factors for complex human disorders. However, the feasibility of large-scale genotyping experiments is currently limited by an incomplete marker coverage of the genome, a restricted understanding of the functional role of given genomic regions, and the small sample sizes used. Thus, genome-wide association analysis...
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