Article
Factor V Leiden and increased risk for arterial thrombotic disease in young Brazilian patients.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2006
de Paula Sabino Adriano, Ribeiro Daniel Dias, Carvalho Maria das Graças, Cardoso Jarbas, Dusse Luci Maria Sant'Ana, Fernandes Ana Paula
Abstract excerpt
The contribution of mutations in the prothrombin (FII G20210A), methylenetetrahydrofolate reductase (C677T) genes and factor V Leiden (FVL) to the pathogenesis of arterial thrombosis remains controversial. In this study, these polymorphisms were investigated by polymerase chain reaction-restriction fragment length polymorphism in a group of 53 patients that presented arterial thrombosis other than myocardial...
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