Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR (C677T, A1298C), FV Leiden polymorphisms, and the prothrombin G20210A mutation in arterial ischemic stroke among young tunisian adults.

Metabolic brain disease - 1 Mar 2021

M'barek Lamia, Sakka Salma, Meghdiche Fatma, Turki Dhaker, Maalla Khadija, Dammak Mariem, Kallel Choumous, Mhiri Chokri

Abstract excerpt

Arterial ischemic stroke (AIS) in young adults is less common in older adults, but the underlying pathogenesis and risk factors are more multi-faceted. The role of inherited thrombophilia such as 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism, (C677T and A1298C), factor V of Leiden (FVL) polymorphism, and the prothrombin G20210A mutations remains unclear. This study aims to evaluate the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Factor V

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ischemic Stroke

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Share to Prothrombin

Share to Tunisia

Share to Young Adult

Source

Identifiers

PMID: 33400068
DOI: 10.1007/s11011-020-00663-7

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR (C677T, A1298C), FV Leiden polymorphisms, and the prothrombin G20210A mutation in arterial ischemic stroke among young tunisian adults.PMID 33400068Read ↗

Hereditary thrombophilic factors in stroke due to cerebral infarct.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients.Semantic proximity Read ↗

Association Between the G20210A Polymorphism of Prothrombin Gene and Myocardial Infarction in Tunisian Population.Semantic proximity Read ↗

The role of classic risk factors and prothrombotic factor gene mutations in ischemic stroke risk development in young and middle-aged individuals.Semantic proximity Read ↗

Association study between genetic polymorphisms in MTHFR and stroke susceptibility in Egyptian population: a case-control study.Semantic proximity Read ↗

Factor V Leiden, prothrombin 20210G>A, MTHFR 677C>T and 1298A>C, and homocysteinemia in Tunisian blood donors.Semantic proximity Read ↗

Polymorphisms in prothrombotic genes in young stroke patients in Greece: a case-controlled study.Semantic proximity Read ↗

Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.Semantic proximity Read ↗

Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke.Semantic proximity Read ↗

Association between Factor V Gene Polymorphism and Risk of Ischemic Stroke: An Updated Meta-Analysis.Semantic proximity Read ↗

Angiotensin converting enzyme polymorphism and ischemic stroke.Semantic proximity Read ↗

Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.