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Article

Increased Factor V Leiden frequency is associated with venous thrombotic events among young Brazilian patients.

Journal of thrombosis and thrombolysis - 1 Dec 2007

de Paula Sabino Adriano, Guimarães Daniela Amorim Melgaço, Ribeiro Daniel Dias, Paiva Sabrina Guimarães, Sant'Ana Dusse Luci Maria, das Graças Carvalho Maria, Fernandes Ana Paula

Abstract excerpt

INTRODUCTION: Of the inherited thrombophilias, the Factor V Leiden (FVL) and the prothrombin mutant (FII G20210A) are associated with increased risk of venous thromboembolism (VTE). The C677T mutation of the methylenetetrahydrofolate reductase gene, which may lead to hyperhomocysteinemia, is also considered a risk factor for VTE in some studies. However, the frequency of these genetic risk factors may vary...

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Identifiers

PMID: 17401546
DOI: 10.1007/s11239-007-0024-x

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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